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Talks of 2014

  1. IAS-IHPST Workshop: Boundaries and levels of biological organization

    The workshop will discuss the notion of biological organization from a systemic- perspective. In particular it will focus on its intrinsic hierarchical dimension, and on the role organization plays in the understanding of the transition from pre-biotic to minimal living systems and of more complex …

  2. A Novel 3D Model to Study the Link Between Hormonal Exposure and Mammographic Density in Breast Cancer

    Lower type 1 collagen concentration (0.5 mg/ml) increases elongation of structures compared to 1 mg/ml. Fibroblasts enhances elongation of structures in 1 mg/ml, but not 0.5 mg/ml. In 1 mg/ml collagen, elongated epithelial structures had lumen formation when co­‐cultured with fibroblasts. Hormones …

  3. Development of Software for Automated Morphology Analysis (SAMA) to analyze morphogenic effects of mammotrophic hormones in vitro

    In vitro 3D simulations of biological systems are critical for understanding morphogenesis and patterns of normal and abnormal development in tissues. <br> Here we present SAMA, a novel method through which epithelial structures grown in 3D cultures can be imaged, reconstructed in 3D and analyzed with …

  4. The specificity of biological objects. From physics to biology tier 2.

    • M Montévil
    • en
    • School of Science and Technology

    The coupling of generic objects, defined by their symmetries, on the one side, and the corresponding trajectories, on the other side, is at the core of the objectivation of phenomena understood in existing physical theories. As for proper biological phenomena, we hypothesize that they do not possess…

  5. Some aspects of biological time. From physics to biology tier 1.

    • M Montévil
    • en
    • School of Science and Technology

    In this talk, we will discuss some propositions of extensions of physical theories to understand biological objects. we will focus on some aspects of biological time. First, we will focus on biological rhythms, in relationship with allometric relations. Then we will discuss the notions of biological…

  6. Biological objects and measurement

    The core of the objectivization in physics is the coupling of generic objects, as defined by their symmetries, and their corresponding specific trajectories. As for biological phenomena, we posit that they do not possess stable theoretical symmetries. Thus, biological objects are specific in the sense…