Jump to main content

A Novel 3D Model to Study the Link Between Hormonal Exposure and Mammographic Density in Breast Cancer

A Novel 3D Model to Study the Link Between Hormonal Exposure and Mammographic Density in Breast Cancer

Cover slide from the talk “A Novel 3D Model to Study the Link Between Hormonal Exposure and Mammographic Density in Breast Cancer”

Lower type 1 collagen concentration (0.5 mg/ml) increases elongation of structures compared to 1 mg/ml. Fibroblasts enhances elongation of structures in 1 mg/ml, but not 0.5 mg/ml. In 1 mg/ml collagen, elongated epithelial structures had lumen formation when co­‐cultured with fibroblasts. Hormones in co-­‐cultures of T47D + fibroblasts, significantly altered the phenotype in terms of elongation.

Paulose, Tessie, Maël Montévil, Lucia Speroni, Carlos Sonnenschein, and Ana M. Soto. 2014. “A Novel 3D Model to Study the Link Between Hormonal Exposure and Mammographic Density in Breast Cancer.” Poster. 16th International Congress of Endocrinology and Endocrine Society’s 96th Annual Meeting & Expo ICE/ENDO 2014, Chicago. https://academic.oup.com/edrv/issue/35/Supplement
Poster.