Jump to main content

Development of Software for Automated Morphology Analysis (SAMA) to analyze morphogenic effects of mammotrophic hormones in vitro

Cover slide from the talk “Development of Software for Automated Morphology Analysis (SAMA) to analyze morphogenic effects of mammotrophic hormones in vitro”

In vitro 3D simulations of biological systems are critical for understanding morphogenesis and patterns of normal and abnormal development in tissues.
Here we present SAMA, a novel method through which epithelial structures grown in 3D cultures can be imaged, reconstructed in 3D and analyzed with minimum human intervention and, therefore, bias.
SAMA gives us an accurate picture of the epithelial structures and hence, more information compared to 2D morphometric analysis. In addition, this automated method is less time consuming than regular 2D morphometrics.

Speroni, Lucia, Maël Montévil, Tessie Paulose, Florent Cerruti, Carlos Sonnenschein, and Ana M. Soto. 2014. “Development of Software for Automated Morphology Analysis (SAMA) to Analyze Morphogenic Effects of Mammotrophic Hormones in Vitro.” Poster. 16th International Congress of Endocrinology and Endocrine Society’s 96th Annual Meeting & Expo ICE/ENDO 2014, Chicago. https://academic.oup.com/edrv/issue/35/Supplement
Poster.