Why should we invest in the concept of entropy to face the challenges of the Anthropocene? Of course, entropy production is a more accurate description of physical processes than energy consumption – and the difference between the two concepts has applications. However, entropy has other ramifications. Living beings oppose entropy increase in two different ways. First, as emphasized by Schrödinger, living beings have to sustain a low entropy situation, and this implies that they are local, open systems. Second, while entropy increase leads to more generic configurations, biological individuation brings about the more specific organization, at the scale of evolution as well as shorter time scales. These specific organizations are precisely the way living being delay the increase of entropy. These counter-trends are analyzed as anti-entropy and anti-entropy production, respectively. We will show that they are damaged in the Anthropocene, meaning that biological organizations are disrupted, and their ability to reorganize is also weakened.